MSS201956

• Gene Symbol: Alox15
• Gene Name: arachidonate 15-lipoxygenase
• Gene Aliases: 12-LO, 12/15-LO, 15-LOX, Alox12l, L-12LO
• Chromosome Location: Chr.11: 70344147 - 70375918 on Build GRCm38
• UniGene ID: Mm.4584
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Alox15
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009660.3	NP_033790.3	13	1786
GenBank mRNA	AK142371.1	-	13	1787
	BC056625.1	-	13	1773	5005087
	BC081546.1	-	13	1772	3671948
	CT010263.1	-	13	1760
	L34570.1	-	13	1770
	U04331.1	-	13	1760

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031010, XM_006246823, XM_006246824, FQ233819, L06040, and others.

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

ossification
negative regulation of adaptive immune response
lipid metabolic process
fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
phosphatidylinositol-4,5-bisphosphate binding
lipid binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity
dioxygenase activity