MSS206158

• Gene Symbol: Tlr7
• Gene Name: toll-like receptor 7
• Gene Aliases: -
• Chromosome Location: Chr.X: 167304926 - 167330574 on Build GRCm38
• UniGene ID: Mm.23979
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tlr7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001290755.1	NP_001277684.1	5	2036
	NM_001290756.1	NP_001277685.1	4	1955
	NM_001290757.1	NP_001277686.1	3	1923
	NM_001290758.1	NP_001277687.1	4	1968
	NM_133211.4	NP_573474.1	3	1887
GenBank mRNA	AF334942.1	-	3	1830
	AF334943.1	-	3	1844
	AK036549.1	-	3	1845
	AK154906.1	-	5	1994
	AK156908.1	-	3	1891
	AY035889.1	-	2	1704
	BC120596.1	-	2	1749	40129519
	BC132385.1	-	3	1817	40130662

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_016562, BC033651, AF240467, AF245702, AK313858, and others.
This siRNA also targets the following transcripts in Rat: NM_001097582, XM_008773170, XM_006256843, XM_006256842, EF032637.

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
immune system process
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
immune response
signal transduction
I-kappaB phosphorylation
positive regulation of chemokine production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
toll-like receptor 7 signaling pathway
positive regulation of NF-kappaB import into nucleus
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of interleukin-8 biosynthetic process
defense response to virus

Function(s)

double-stranded RNA binding
single-stranded RNA binding
transmembrane signaling receptor activity
protein binding
drug binding
siRNA binding