MSS206506

• Gene Symbol: Mapkapk2
• Gene Name: MAP kinase-activated protein kinase 2
• Gene Aliases: AA960234, MAPKAP-K2, MK-2, MK2, Rps6kc1
• Chromosome Location: Chr.1: 131053700 - 131097543 on Build GRCm38
• UniGene ID: Mm.221235
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Mapkapk2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008551.1	NP_032577.1	3	443
GenBank mRNA	AK188700.1	-	3	230
	BC063064.1	-	3	443	5687007
	X76850.1	-	3	422

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_032960, NM_004759, BC036060, X75346, BC052584, and others.
This siRNA also targets the following transcripts in Rat: NM_178102, BC062048, AY197741.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
protein phosphorylation
response to stress
inflammatory response
cellular response to DNA damage stimulus
phosphorylation
peptidyl-serine phosphorylation
G2 DNA damage checkpoint
response to lipopolysaccharide
regulation of interleukin-6 production
regulation of tumor necrosis factor production
response to cytokine
cellular response to vascular endothelial growth factor stimulus
p38MAPK cascade
positive regulation of tumor necrosis factor biosynthetic process
macropinocytosis
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
mRNA stabilization
inner ear development
3'-UTR-mediated mRNA stabilization

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
signal transducer activity
protein binding
calmodulin binding
ATP binding
calcium-dependent protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase binding