MSS207518

• Gene Symbol: Pdpk1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: Pdk1
• Chromosome Location: Chr.17: 24073680 - 24150922 on Build GRCm38
• UniGene ID: Mm.10504
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdpk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001080773.2	NP_001074242.1	10	1151
	NM_001286662.1	NP_001273591.1	10	1069
	NM_011062.4	NP_035192.2	10	1151
GenBank mRNA	AF079535.1	-	10	1108
	AF086625.1	-	10	1117
	AF126294.1	-	10	1092
	AK147149.1	-	10	1143
	AK147835.1	-	10	1126
	AK149162.1	-	10	1085
	AK149289.1	-	10	1109
	AK162677.1	-	10	1111
	AK165564.1	-	10	1088
	AK188106.1	-	2	119
	AK205439.1	-	1	64
	AK219503.1	-	2	78
	AY062008.1	-	10	1047
	BC146001.1	-	10	1088	40131304
	BC146003.1	-	10	1088	40131306

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031081, XM_006246036, XM_006246038, Y15748.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
phosphorylation
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
phospholipase binding