MSS208566

• Gene Symbol: Rbpj
• Gene Name: recombination signal binding protein for immunoglobulin kappa J region
• Gene Aliases: AI843960, CBF1, Igkjrb, Igkrsbp, RBP-J, RBP-J kappa, RBPjk, Rbpsuh
• Chromosome Location: Chr.5: 53466117 - 53657445 on Build GRCm38
• UniGene ID: Mm.209292
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Rbpj
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001080927.2	NP_001074396.1	8	1012
	NM_001080928.1	NP_001074397.1	8	898
	NM_001277116.1	NP_001264045.1	10	1094
	NM_009035.5	NP_033061.3	8	914
GenBank mRNA	AK028363.1	-	10	1072
	AK080359.1	-	8	807
	AK090006.1	-	8	799
	AK139087.1	-	8	799
	AK145187.1	-	8	806
	AK152746.1	-	8	914
	AK153163.1	-	9	802
	BC035299.1	-	6	700
	BC051387.1	-	8	843	4460290
	S63463.1	-	8	915
	X17459.1	-	8	910

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106631, XM_008770190, XM_008770193, XM_008770191, XM_006237737, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
somitogenesis
epithelial to mesenchymal transition
heart looping
blood vessel remodeling
inflammatory response to antigenic stimulus
secondary heart field specification
outflow tract morphogenesis
endocardium development
endocardium morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
cardiac left ventricle morphogenesis
ventricular trabecula myocardium morphogenesis
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
humoral immune response
Notch signaling pathway
positive regulation of transcription of Notch receptor target
heart development
positive regulation of cell proliferation
negative regulation of cell proliferation
auditory receptor cell fate commitment
epidermal cell fate specification
regulation of gene expression
positive regulation of gene expression
negative regulation of neuron projection development
negative regulation of smooth muscle cell migration
pituitary gland development
hemopoiesis
neuron differentiation
B cell differentiation
keratinocyte differentiation
negative regulation of ossification
positive regulation of BMP signaling pathway
negative regulation of smooth muscle cell apoptotic process
somatic stem cell population maintenance
positive regulation of Notch signaling pathway involved in heart induction
dorsal aorta morphogenesis
atrioventricular canal development
defense response to bacterium
myeloid dendritic cell differentiation
cell fate commitment
negative regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of timing of cell differentiation
positive regulation of smooth muscle cell proliferation
sebaceous gland development
hair follicle maturation
artery morphogenesis
positive regulation of cardiac muscle cell proliferation
Clara cell differentiation
labyrinthine layer blood vessel development
arterial endothelial cell fate commitment
Notch signaling pathway involved in arterial endothelial cell fate commitment
regulation of cell adhesion involved in heart morphogenesis
determination of heart left/right asymmetry
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
blood vessel lumenization
interleukin-4 secretion
blood vessel endothelial cell fate specification
positive regulation of ERBB signaling pathway
positive regulation of ephrin receptor signaling pathway
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
positive regulation of cell proliferation involved in heart morphogenesis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
sequence-specific DNA binding
protein N-terminus binding