MSS209197

• Gene Symbol: Smarca4
• Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
• Gene Aliases: Brg1, HP1-BP72, SNF2beta, SW1/SNF, b2b508.1Clo, b2b692Clo
• Chromosome Location: Chr.9: 21616106 - 21704230 on Build GRCm38
• UniGene ID: Mm.286593
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smarca4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001174078.1	NP_001167549.1	26	3888
	NM_001174079.1	NP_001167550.1	26	3888
	NM_011417.3	NP_035547.2	26	3888
GenBank mRNA	AK141517.1	-	23	3042
	AK147047.1	-	11	1204
	AK147285.1	-	26	3842
	AK160825.1	-	26	3792
	AK166837.1	-	26	3793
	BC023186.1	-	5	477
	BC026672.1	-	9	1037
	BC060229.1	-	26	3782
	BC079560.1	-	26	3888	30533489
	S68108.1	-	16	1854

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
blood vessel development
vasculogenesis
in utero embryonic development
blastocyst growth
blastocyst hatching
liver development
outflow tract morphogenesis
nucleosome assembly
nucleosome disassembly
chromatin remodeling
methylation-dependent chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
nervous system development
glial cell fate determination
heart development
positive regulation of cell proliferation
DNA methylation on cytosine within a CG sequence
chromatin modification
stem cell population maintenance
neurogenesis
positive regulation of Wnt signaling pathway
extracellular matrix organization
keratinocyte differentiation
negative regulation of cell growth
regulation of cell migration
forebrain development
hindbrain development
embryonic hindlimb morphogenesis
aortic smooth muscle cell differentiation
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
positive regulation of DNA binding
positive regulation by host of viral transcription
histone H3 acetylation
positive regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic organ morphogenesis
epidermis morphogenesis
positive regulation of sequence-specific DNA binding transcription factor activity
definitive erythrocyte differentiation
heart trabecula formation
negative regulation of androgen receptor signaling pathway
pharyngeal arch artery morphogenesis
lens fiber cell development
positive regulation of pri-miRNA transcription from RNA polymerase II promoter

Function(s)

nucleotide binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription coactivator activity
p53 binding
DNA binding
chromatin binding
transcription coactivator activity
transcription corepressor activity
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
transcription factor binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
ATPase activity
Tat protein binding
nucleosomal DNA binding
protein complex binding
histone binding
protein N-terminus binding
androgen receptor binding
DNA polymerase binding
lysine-acetylated histone binding