MSS212282

• Gene Symbol: Nr1h3
• Gene Name: nuclear receptor subfamily 1, group H, member 3
• Gene Aliases: AU018371, LXR, RLD1, Unr1
• Chromosome Location: Chr.2: 91184061 - 91202834 on Build GRCm38
• UniGene ID: Mm.22690
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr1h3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001177730.1	NP_001171201.1	3	253
	NM_013839.4	NP_038867.2	3	406
GenBank mRNA	AF085745.1	-	3	148
	AJ132601.1	-	3	184
	AK143904.1	-	3	187
	AK159250.1	-	3	407
	AY195870.1	-	3	253
	AY195871.1	-	3	253
	BC012646.1	-	3	194	4163109

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031627, XM_006234537, XM_006234535, XM_006234533, XM_008762013, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
fatty acid biosynthetic process
positive regulation of triglyceride biosynthetic process
positive regulation of receptor biosynthetic process
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
response to progesterone
positive regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
negative regulation of macrophage activation
apoptotic cell clearance
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of pinocytosis
negative regulation of inflammatory response
positive regulation of lipoprotein lipase activity
lipid homeostasis
sterol homeostasis
triglyceride homeostasis
cellular response to lipopolysaccharide
negative regulation of pancreatic juice secretion
negative regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis
positive regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
retinoid X receptor binding
protein heterodimerization activity