MSS212822

• Gene Symbol: Ticam2
• Gene Name: toll-like receptor adaptor molecule 2
• Gene Aliases: B430113A10, TICAM-2, TRAM, Tirp, Trif
• Chromosome Location: Chr.18: 46558231 - 46574533 on Build GRCm38
• UniGene ID: Mm.149280
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ticam2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_173394.3	NP_775570.1	3	489
GenBank mRNA	AB100441.1	-	2	132
	AK080873.1	-	3	262
	AK134103.1	-	3	490
	AK151885.1	-	3	466
	AY268050.1	-	1	13
	AY275837.1	-	3	488
	BC099933.1	-	3	488	30017195

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108890, XM_006254690.

Panther Classification:

Molecular Function -

vesicle coat protein

Gene Ontology Categories:

Process(es)

regulation of cytokine production
immune system process
inflammatory response
signal transduction
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
negative regulation of toll-like receptor 4 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
TRAM-dependent toll-like receptor 4 signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of interferon-beta biosynthetic process
response to interleukin-12
cellular response to lipopolysaccharide
negative regulation of chemokine (C-C motif) ligand 5 production
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of interleukin-18-mediated signaling pathway

Function(s)

signal transducer activity
interleukin-1 receptor binding
protein binding
phospholipid binding
protein heterodimerization activity