MSS230423

• Gene Symbol: Ubr5
• Gene Name: ubiquitin protein ligase E3 component n-recognin 5
• Gene Aliases: Edd, Edd1
• Chromosome Location: Chr.15: 37967328 - 38078854 on Build GRCm38
• UniGene ID: Mm.476840
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ubr5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001081359.3	NP_001074828.2	39	5750
	NM_001112721.2	NP_001106192.1	39	5732
GenBank mRNA	AK122398.1	-	16	2223
	AY550908.1	-	39	5340
	BC047348.1	-	30	4243
	BC049162.1	-	10	1430

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_006241570, XM_008765468, XM_008765469.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein polyubiquitination
DNA repair
cellular response to DNA damage stimulus
positive regulation of protein import into nucleus, translocation
positive regulation of catenin import into nucleus
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
progesterone receptor signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of histone H2A K63-linked ubiquitination
negative regulation of double-strand break repair

Function(s)

RNA binding
ubiquitin-protein transferase activity
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
ubiquitin-ubiquitin ligase activity
ubiquitin binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity