MSS233776

• Gene Symbol: Gper1
• Gene Name: G protein-coupled estrogen receptor 1
• Gene Aliases: 6330420K13Rik, CMKRL2, Ceprl, FEG-1, GPCR-Br, Gper, Gpr30
• Chromosome Location: Chr.5: 139422972 - 139427800 on Build GRCm38
• UniGene ID: Mm.389706
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gper1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_029771.3	NP_084047.2	3	1063
GenBank mRNA	AK018203.1	-	3	967
	AK030375.1	-	3	1064
	BC138598.1	-	3	918	8861618
	BC138616.1	-	3	918	8861636

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_133573, XM_006248914, U92802.

• Set Membership: G-protein coupled receptor

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
immune system process
negative regulation of leukocyte activation
transcription from RNA polymerase II promoter
apoptotic process
inflammatory response
cell cycle
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
nervous system development
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
cell differentiation
apoptotic chromosome condensation
nuclear fragmentation involved in apoptotic nuclear change
positive regulation of cell migration
intracellular steroid hormone receptor signaling pathway
positive regulation of cAMP biosynthetic process
mineralocorticoid receptor signaling pathway
positive regulation of insulin secretion
positive regulation of inositol trisphosphate biosynthetic process
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
steroid hormone mediated signaling pathway
positive regulation of MAPK cascade
innate immune response
negative regulation of fat cell differentiation
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of vasodilation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
positive regulation of neurogenesis
negative regulation of DNA metabolic process
negative regulation of lipid biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of ERK1 and ERK2 cascade
positive regulation of uterine smooth muscle contraction
negative regulation of cell cycle arrest
cellular response to glucose stimulus
cellular response to tumor necrosis factor
cellular response to peptide hormone stimulus
cellular response to mineralocorticoid stimulus
cellular response to estradiol stimulus
positive regulation of establishment of protein localization to plasma membrane
positive regulation of release of cytochrome c from mitochondria
positive regulation of endothelial cell apoptotic process
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

chromatin binding
steroid hormone receptor activity
signal transducer activity
G-protein coupled receptor activity
steroid binding
drug binding
mineralocorticoid receptor activity
estrogen receptor activity
hormone binding