MSS236016

• Gene Symbol: Axin2
• Gene Name: axin2
• Gene Aliases: Axi1, Axil, Conductin
• Chromosome Location: Chr.11: 108917828 - 108950783 on Build GRCm38
• UniGene ID: Mm.71710
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Axin2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015732.4	NP_056547.3	10	2717
GenBank mRNA	AF073788.1	-	10	2582
	AF205889.1	-	9	2422
	AK049192.1	-	10	2662
	AK084644.1	-	3	502
	AK198476.1	-	2	238
	AK202759.1	-	2	238
	BC057338.1	-	10	2700	6827741

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_024355, AF017757.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

somitogenesis
positive regulation of protein phosphorylation
intramembranous ossification
secondary heart field specification
chondrocyte differentiation involved in endochondral bone morphogenesis
regulation of transcription, DNA-templated
cell death
cell proliferation
negative regulation of cell proliferation
dorsal/ventral axis specification
positive regulation of epithelial to mesenchymal transition
positive regulation of cell death
Wnt signaling pathway
regulation of Wnt signaling pathway
bone mineralization
regulation of mismatch repair
cellular protein localization
regulation of catenin import into nucleus
negative regulation of catenin import into nucleus
termination of G-protein coupled receptor signaling pathway
odontogenesis
positive regulation of GTPase activity
maintenance of DNA repeat elements
negative regulation of osteoblast differentiation
positive regulation of protein kinase activity
mRNA stabilization
regulation of chondrocyte development
regulation of centromeric sister chromatid cohesion
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Function(s)

GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
ubiquitin protein ligase binding
armadillo repeat domain binding
I-SMAD binding