MSS236620

• Gene Symbol: Gja1
• Gene Name: gap junction protein, alpha 1
• Gene Aliases: AU042049, AW546267, Cnx43, Cx43, Cx43alpha1, Gja-1, Npm1, connexin43
• Chromosome Location: Chr.10: 56377201 - 56390423 on Build GRCm38
• UniGene ID: Mm.378921
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gja1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010288.3	NP_034418.1	2	958
GenBank mRNA	AK029291.1	-	2	815
	AK036979.1	-	2	929
	AK145692.1	-	2	928
	AK165986.1	-	2	815
	AK171955.1	-	2	926
	BC006894.1	-	2	911	3599347
	BC011324.1	-	2	1040
	BC055375.1	-	2	881	30063597
	CT010327.1	-	1	726
	M63801.1	-	2	946
	X61576.1	-	2	812

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012567, XM_006256503, AY324140, BC081842.

Panther Classification:

Molecular Function -

gap junction

Gene Ontology Categories:

Process(es)

osteoblast differentiation
in utero embryonic development
neuron migration
negative regulation of endothelial cell proliferation
heart looping
regulation of heart rate
epithelial cell maturation
lens development in camera-type eye
chronic inflammatory response
positive regulation of glomerular filtration
atrial ventricular junction remodeling
epicardial cell to mesenchymal cell transition
apoptotic process
cell communication
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
heart development
adult heart development
regulation of heart contraction
negative regulation of cell proliferation
response to pH
vascular transport
positive regulation of gene expression
negative regulation of gene expression
cell communication by chemical coupling
cell communication by electrical coupling
positive regulation of cell communication by chemical coupling
ATP transport
regulation of bone mineralization
positive regulation of insulin secretion
ion transmembrane transport
embryonic heart tube development
embryonic digit morphogenesis
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
cell-cell junction organization
positive regulation of osteoblast differentiation
positive regulation of protein catabolic process
positive regulation of striated muscle tissue development
positive regulation of vasoconstriction
positive regulation of vasodilation
regulation of bone remodeling
blood vessel morphogenesis
neuron projection morphogenesis
protein oligomerization
regulation of calcium ion transport
transmembrane transport
negative regulation of cardiac muscle cell proliferation
milk ejection
regulation of ventricular cardiac muscle cell membrane repolarization
regulation of blood vessel remodeling
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
negative regulation of wound healing
cardiac conduction
establishment of epithelial cell polarity
negative regulation of DNA biosynthetic process
regulation of bicellular tight junction assembly
positive regulation of behavioral fear response

Function(s)

signal transducer activity
receptor binding
gap junction channel activity
protein binding
ion transmembrane transporter activity
SH3 domain binding
protein domain specific binding
transmembrane transporter activity
PDZ domain binding
beta-tubulin binding
connexin binding
scaffold protein binding
gap junction channel activity involved in cell communication by electrical coupling