MSS237530

• Gene Symbol: Pdgfa
• Gene Name: platelet derived growth factor, alpha
• Gene Aliases: -
• Chromosome Location: Chr.5: 138976381 - 138999916 on Build GRCm38
• UniGene ID: Mm.2675
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdgfa
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_008808.3	NP_032834.1	2	327
GenBank mRNA	AY324648.1	-	2	316
	BC003817.1	-	2	327	3495629
	M29464.1	-	2	207

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012801, XM_008768940, XM_006248919, XM_006248918, Z14120, and others.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

angiogenesis
hair follicle development
positive regulation of mesenchymal cell proliferation
multicellular organism development
positive regulation of cell proliferation
response to wounding
organ morphogenesis
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
positive regulation of phosphatidylinositol 3-kinase signaling
regulation of smooth muscle cell migration
cell projection assembly
actin cytoskeleton organization
positive regulation of cell migration
positive regulation of protein autophosphorylation
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
skin development
positive regulation of DNA replication
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
lung alveolus development
digestive tract development
regulation of peptidyl-tyrosine phosphorylation
negative chemotaxis
positive regulation of cell division
positive regulation of protein kinase B signaling
bone development
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
positive regulation of ERK1 and ERK2 cascade
embryonic lung development

Function(s)

platelet-derived growth factor receptor binding
collagen binding
growth factor activity
protein homodimerization activity
protein heterodimerization activity
platelet-derived growth factor binding