MSS239495

• Gene Symbol: Ago2
• Gene Name: argonaute RISC catalytic subunit 2
• Gene Aliases: 1110029L17Rik, 2310051F07Rik, AI225898, AL022874, AW546247, ENSMUSG00000072493, Eif2c2, Gerp95, Gm10365, mKIAA4215
• Chromosome Location: Chr.15: 73101625 - 73184947 on Build GRCm38
• UniGene ID: Mm.23095
• Species: Mouse

siRNA Details

Gene Symbol: Ago2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_153178.4	NP_694818.3	11	1557
GenBank mRNA	AB081472.1	-	11	1419
	AK220193.1	-	8	922
	BC023279.1	-	3	259
	BC024857.1	-	4	402
	BC056639.1	-	1	124
	BC064741.1	-	6	674
	BC096465.1	-	11	1462
	BC128379.1	-	11	1410	40111876
	BC129922.1	-	11	1410	40111875

More Information

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA cleavage
regulation of translation
multicellular organism development
post-embryonic development
RNA secondary structure unwinding
miRNA metabolic process
positive regulation of gene expression
cell differentiation
gene silencing by RNA
pre-miRNA processing
siRNA loading onto RISC involved in RNA interference
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
RNA phosphodiester bond hydrolysis, endonucleolytic
mRNA cleavage involved in gene silencing by siRNA
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Function(s)

RNA 7-methylguanosine cap binding
RNA polymerase II core binding
core promoter binding
nucleic acid binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
mRNA binding
nuclease activity
endonuclease activity
endoribonuclease activity
protein binding
hydrolase activity
siRNA binding
miRNA binding
poly(A) RNA binding
metal ion binding
endoribonuclease activity, cleaving siRNA-paired mRNA
pre-miRNA binding
endoribonuclease activity, cleaving miRNA-paired mRNA