MSS246642

• Gene Symbol: Tlr9
• Gene Name: toll-like receptor 9
• Gene Aliases: -
• Chromosome Location: Chr.9: 106222598 - 106226876 on Build GRCm38
• UniGene ID: Mm.44889
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tlr9
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031178.2	NP_112455.2	2	1786
GenBank mRNA	AB045181.1	-	2	1786
	AF348140.1	-	2	1719

More Information

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
response to molecule of bacterial origin
immune system process
regulation of dendritic cell cytokine production
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
immune response
signal transduction
I-kappaB phosphorylation
response to virus
positive regulation of autophagy
positive regulation of gene expression
maintenance of gastrointestinal epithelium
negative regulation of NF-kappaB transcription factor activity
tumor necrosis factor production
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of chemokine production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-beta production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-18 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
positive regulation of toll-like receptor signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
regulation of cytokine secretion
regulation of inflammatory response
positive regulation of inflammatory response
defense response to Gram-negative bacterium
regulation of B cell activation
positive regulation of NF-kappaB transcription factor activity
defense response to virus
positive regulation of nitric-oxide synthase biosynthetic process
negative regulation of calcium-transporting ATPase activity

Function(s)

transmembrane signaling receptor activity
interleukin-1 receptor binding
protein binding
siRNA binding
unmethylated CpG binding