MSS273605

• Gene Symbol: Cdkn1b
• Gene Name: cyclin-dependent kinase inhibitor 1B
• Gene Aliases: AA408329, AI843786, Kip1, p27, p27Kip1
• Chromosome Location: Chr.6: 134920401 - 134925525 on Build GRCm38
• UniGene ID: Mm.2958
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cdkn1b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009875.4	NP_034005.2	1	773
GenBank mRNA	AK046676.1	-	1	508
	AK047669.1	-	1	774
	AK050240.1	-	1	760
	AK158411.1	-	1	753
	AK162146.1	-	1	493
	BC014296.1	-	1	756	4193493
	CT010382.1	-	1	254
	U09968.1	-	1	254
	U10440.1	-	1	471

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004064, U10906, AJ616234, BC001971, AK298335, and others.
This siRNA also targets the following transcripts in Rat: NM_031762, XM_006237539, D83792, AY623024, AY623040, and others.

Panther Classification:

Molecular Function -

kinase inhibitor

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
potassium ion transport
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell cycle
cell cycle arrest
Notch signaling pathway
sensory perception of sound
cell death
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of cell death
negative regulation of cell growth
positive regulation of microtubule polymerization
negative regulation of kinase activity
regulation of cell proliferation
negative regulation of phosphorylation
negative regulation of apoptotic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
autophagic cell death
inner ear development
negative regulation of epithelial cell proliferation
negative regulation of cellular component movement
negative regulation of epithelial cell proliferation involved in prostate gland development
cellular response to antibiotic
cellular response to lithium ion
cellular response to organic cyclic compound
mitotic cell cycle arrest

Function(s)

protein kinase inhibitor activity
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein binding
cysteine-type endopeptidase activator activity involved in apoptotic process
protein phosphatase binding
Hsp70 protein binding
protein complex binding
chaperone binding