MSS274094

• Gene Symbol: Egf
• Gene Name: epidermal growth factor
• Gene Aliases: AI790464
• Chromosome Location: Chr.3: 129677569 - 129755322 on Build GRCm38
• UniGene ID: Mm.252481
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Egf
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010113.3	NP_034243.2	2	571
GenBank mRNA	AK084927.1	-	2	566
	AK085707.1	-	2	138
	AK142666.1	-	2	267
	BC017681.1	-	3	508	4221592
	BC060741.1	-	2	556	4164289
	BC092277.1	-	2	556	4240429
	J00380.1	-	2	566
	V00741.1	-	2	522

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012842, XM_008760814, XM_008760815, XM_008760816, JX149564, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
angiogenesis
epidermal growth factor receptor signaling pathway
STAT protein import into nucleus
positive regulation of cell proliferation
positive regulation of peptidyl-threonine phosphorylation
peptidyl-tyrosine phosphorylation
positive regulation of cerebellar granule cell precursor proliferation
positive regulation of catenin import into nucleus
positive regulation of phosphorylation
positive regulation of DNA binding
positive regulation of MAP kinase activity
positive regulation of epidermal growth factor-activated receptor activity
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
branching morphogenesis of an epithelial tube
regulation of protein secretion
regulation of peptidyl-tyrosine phosphorylation
negative regulation of secretion
regulation of protein transport
mammary gland alveolus development
ERK1 and ERK2 cascade
regulation of calcium ion import
negative regulation of cholesterol efflux
positive regulation of hyaluronan biosynthetic process
regulation of protein localization to cell surface
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Function(s)

epidermal growth factor receptor binding
calcium ion binding
protein binding
growth factor activity