MSS274952

• Gene Symbol: Eif2ak1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: HCR, Hri
• Chromosome Location: Chr.5: 143871862 - 143902717 on Build GRCm38
• UniGene ID: Mm.389709
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Eif2ak1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013557.2	NP_038585.2		508
GenBank mRNA	AK014775.1	-		470
	AK155206.1	-		490
	AK156492.1	-		469
	AK158437.1	-		464
	AK173160.1	-		458
	AY033898.1	-		493
	BB625879.1	-		509
	BC028923.1	-		480	4164417
	BC111035.1	-		459	5357121

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013223, BC081838, L27707.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
regulation of translation
protein phosphorylation
phagocytosis
negative regulation of cell proliferation
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
phosphorylation
negative regulation of translation
macrophage differentiation
protoporphyrinogen IX metabolic process
regulation of hemoglobin biosynthetic process
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
heme binding
protein homodimerization activity