MSS275938

• Gene Symbol: Nck1
• Gene Name: non-catalytic region of tyrosine kinase adaptor protein 1
• Gene Aliases: 6330586M15Rik, D230010O13Rik, Nck, Nck-1
• Chromosome Location: Chr.9: 100494981 - 100546053 on Build GRCm38
• UniGene ID: Mm.181485
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nck1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_010878.2	NP_035008.2	2	202
GenBank mRNA	AF043259.1	-	2	290
	AF084183.1	-	1	125
	BC002015.1	-	2	202	3593441

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_006153, BC006403, X17576, AK312692, DA265476.
This siRNA also targets the following transcripts in Rat: NM_001106851, BC167009.

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

regulation of translation
negative regulation of protein kinase activity
substrate-dependent cell migration, cell extension
actin filament organization
cell migration
lamellipodium assembly
positive regulation of actin filament polymerization
negative regulation of peptidyl-serine phosphorylation
positive regulation of translation in response to endoplasmic reticulum stress
positive regulation of T cell proliferation
T cell activation
positive regulation of transcription from RNA polymerase II promoter
response to other organism
negative regulation of cell death
peptidyl-serine dephosphorylation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of cap-dependent translational initiation
positive regulation of cap-independent translational initiation
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

protein kinase inhibitor activity
receptor binding
protein binding
protein kinase regulator activity
protein domain specific binding
receptor tyrosine kinase binding
eukaryotic initiation factor eIF2 binding