MSS276478

• Gene Symbol: Prnp
• Gene Name: prion protein
• Gene Aliases: AA960666, AI325101, CD230, PrP, PrP<C>, PrPC, PrPSc, Prn-i, Prn-p, Sinc, prP27-30, prP33-35C
• Chromosome Location: Chr.2: 131909928 - 131938436 on Build GRCm38
• UniGene ID: Mm.648
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prnp
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001278256.1	NP_001265185.1	4	2361
	NM_011170.3	NP_035300.1	3	820
GenBank mRNA	AK148061.1	-	3	812
	AK148892.1	-	3	781
	AK150963.1	-	3	776
	AK157840.1	-	3	778
	AK158908.1	-	3	797
	AK159056.1	-	4	2325
	AK159224.1	-	3	766
	AK160091.1	-	3	766
	AK162504.1	-	3	784
	BC006703.1	-	2	728	3583938
	BC032085.1	-	2	731
	CT010345.1	-	1	636
	M13685.1	-	2	735

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012631, XM_006235062, BC072692, M20313, FQ211780.

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
nucleobase-containing compound metabolic process
cellular copper ion homeostasis
response to oxidative stress
learning or memory
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-2 production
regulation of protein localization
cellular response to drug
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of activated T cell proliferation
response to cadmium ion
response to copper ion
negative regulation of T cell receptor signaling pathway
protein homooligomerization
negative regulation of calcineurin-NFAT signaling cascade
cellular response to copper ion
regulation of potassium ion transmembrane transport

Function(s)

copper ion binding
protein binding
microtubule binding
tubulin binding
identical protein binding
ATP-dependent protein binding
ion channel binding
metal ion binding
chaperone binding