MSS277025

• Gene Symbol: Spi1
• Gene Name: spleen focus forming virus (SFFV) proviral integration oncogene
• Gene Aliases: Dis-1, Dis1, PU.1, Sfpi-1, Sfpi1, Spi-1, Tcfpu1, Tfpu.1
• Chromosome Location: Chr.2: 91082381 - 91115757 on Build GRCm38
• UniGene ID: Mm.1302
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Spi1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011355.1	NP_035485.1	5	715
GenBank mRNA	AK142246.1	-	5	732
	AK153524.1	-	5	746
	AK154945.1	-	5	767
	AK155085.1	-	5	751
	BC003815.1	-	5	633	3600260
	L03215.1	-	5	612
	M32370.1	-	5	695
	M38252.1	-	5	715
	X17463.1	-	5	1403

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_003120, NM_001080547, X52056, BI519776, BX647491, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
vasculature development
lymphoid progenitor cell differentiation
myeloid leukocyte differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
lymphocyte differentiation
erythrocyte differentiation
macrophage differentiation
granulocyte differentiation
somatic stem cell population maintenance
myeloid dendritic cell differentiation
histone H3 acetylation
hypermethylation of CpG island
negative regulation of MHC class II biosynthetic process
regulation of erythrocyte differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure regression
negative regulation of histone H4 acetylation
apoptotic process involved in patterning of blood vessels

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA binding
protein binding
sequence-specific DNA binding
NFAT protein binding