MSS278349

• Gene Symbol: Thrb
• Gene Name: thyroid hormone receptor beta
• Gene Aliases: Nr1a2, T3R[b], T3Rbeta, Thrb1, Thrb2, c-erbAbeta
• Chromosome Location: Chr.14: 17659218 - 18040097 on Build GRCm38
• UniGene ID: Mm.32563
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Thrb
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001113417.1	NP_001106888.1	8	1032
	NM_009380.3	NP_033406.1	5	1118
GenBank mRNA	AB221613.1	-	5	885
	AK133662.1	-	5	615
	AK158826.1	-	8	1033
	BC089035.1	-	5	1118	30695885
	BC119552.1	-	5	1055	40057420
	BC119553.1	-	5	1059	40057421
	S62756.1	-	7	902

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001128176, NM_001128177, NM_001252634, NM_000461, AI003028, and others.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
sensory perception of sound
negative regulation of female receptivity
regulation of heart contraction
female courtship behavior
positive regulation of cell proliferation
organ morphogenesis
regulation of lipid metabolic process
intracellular receptor signaling pathway
positive regulation of chondrocyte differentiation
steroid hormone mediated signaling pathway
positive regulation of ossification
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
Type I pneumocyte differentiation
regulation of cholesterol metabolic process
regulation of triglyceride metabolic process

Function(s)

DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
thyroid hormone receptor activity
protein binding
zinc ion binding
enzyme binding
chromatin DNA binding
protein homodimerization activity
sequence-specific DNA binding
metal ion binding
thyroid hormone binding