MSS278828

• Gene Symbol: Pak2
• Gene Name: p21 protein (Cdc42/Rac)-activated kinase 2
• Gene Aliases: 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182
• Chromosome Location: Chr.16: 32016290 - 32079342 on Build GRCm38
• UniGene ID: Mm.234204
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pak2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_177326.3	NP_796300.1	2	381
GenBank mRNA	AK037275.1	-	2	382
	AK190087.1	-	1	31
	AY167030.1	-	1	107
	BC063068.1	-		369
	BC086650.1	-	2	312	6849008

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002577, AB209428, AI140979, BC069613, AK291339, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

protein phosphorylation
apoptotic process
Rho protein signal transduction
regulation of mitotic cell cycle
metabolic process
phosphorylation
cell migration
peptidyl-serine phosphorylation
signal transduction by protein phosphorylation
actin cytoskeleton organization
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of growth
negative regulation of apoptotic process
regulation of MAPK cascade
protein autophosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
dendritic spine development
positive regulation of protein tyrosine kinase activity
cellular response to organic cyclic compound
positive regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

nucleotide binding
catalytic activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein tyrosine kinase activator activity
identical protein binding
Rac GTPase binding