MSS279442

• Gene Symbol: Ddx58
• Gene Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
• Gene Aliases: 6430573D20Rik, C330021E21, RIG-I, RLR-1
• Chromosome Location: Chr.4: 40203777 - 40239825 on Build GRCm38
• UniGene ID: Mm.86382
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ddx58
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_172689.3	NP_766277.3	13	1947
GenBank mRNA	AK049305.1	-	4	538
	AK052595.1	-	9	1201
	AK128929.1	-	13	1882
	AK155930.1	-	13	1883
	BC106095.1	-	13	1867
	BC127163.1	-	13	1813
	BC152540.1	-	13	1815

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_014314, BX647917, AL137608, AK301678, BC136610, and others.

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
immune system process
detection of virus
response to virus
positive regulation of gene expression
regulation of cell migration
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
RIG-I signaling pathway
positive regulation of transcription factor import into nucleus
response to exogenous dsRNA
innate immune response
positive regulation of transcription from RNA polymerase II promoter
defense response to virus

Function(s)

nucleotide binding
nucleic acid binding
double-stranded DNA binding
RNA binding
double-stranded RNA binding
single-stranded RNA binding
helicase activity
protein binding
ATP binding
zinc ion binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
identical protein binding
metal ion binding