RSS301297

• Gene Symbol: Sphk1
• Gene Name: sphingosine kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.10: 105498728 - 105504401 on Build Rnor_6.0
• UniGene ID: Rn.18522
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Sphk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001270807.1	NP_001257736.1	6	937
	NM_001270808.1	NP_001257737.1	6	986
	NM_001270809.1	NP_001257738.1	6	887
	NM_001270810.1	NP_001257739.1	6	1573
	NM_001270811.1	NP_001257740.1	6	1923
	NM_133386.3	NP_596877.2	5	2177
	XM_006247787.2	XP_006247849.1	6	1257
	XM_006247788.2	XP_006247850.1	6	768
GenBank mRNA	AB049571.1	-	6	985
	AB049572.1	-	6	937
	AB049573.1	-	6	884
	AB049574.1	-	6	1543
	AB049575.1	-	5	1690
	BC081738.1	-	5	2142	7132896
	DQ486894.1	-	6	725

More Information

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

blood vessel development
positive regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
sphingosine metabolic process
inflammatory response
protein kinase C-activating G-protein coupled receptor signaling pathway
brain development
female pregnancy
positive regulation of cell proliferation
cellular response to starvation
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
response to organic cyclic compound
response to amine
cyclooxygenase pathway
calcium-mediated signaling
positive regulation of cell growth
positive regulation of cell migration
positive regulation of protein ubiquitination
response to magnesium ion
response to progesterone
regulation of interleukin-1 beta production
response to ATP
positive regulation of NF-kappaB import into nucleus
negative regulation of apoptotic process
positive regulation of angiogenesis
positive regulation of mitotic cell cycle
positive regulation of smooth muscle contraction
lipid phosphorylation
positive regulation of fibroblast proliferation
positive regulation of NF-kappaB transcription factor activity
cellular response to hydrogen peroxide
response to interleukin-1
cellular response to growth factor stimulus

Function(s)

magnesium ion binding
DNA binding
NAD+ kinase activity
diacylglycerol kinase activity
protein binding
calmodulin binding
ATP binding
sphinganine kinase activity
D-erythro-sphingosine kinase activity
protein phosphatase 2A binding