RSS303719

• Gene Symbol: Nedd4
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
• Gene Aliases: Nedd4a
• Chromosome Location: Chr.8: 79323408 - 79408842 on Build Rnor_6.0
• UniGene ID: Rn.99540
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nedd4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012986.1	NP_037118.1	9, 10	748
	XM_008766214.1	XP_008764436.1	4, 5	4159
GenBank mRNA	U50842.1	-	9, 10	674

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010890, D85414, AK050517, U96635, AK088767, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
adaptive immune response
outflow tract morphogenesis
endocardial cushion development
protein monoubiquitination
protein targeting to lysosome
immune response
lysosomal transport
neuromuscular junction development
negative regulation of sodium ion transport
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
positive regulation of phosphatidylinositol 3-kinase signaling
response to denervation involved in regulation of muscle adaptation
protein ubiquitination
transmission of virus
negative regulation of vascular endothelial growth factor receptor signaling pathway
neuron projection development
receptor internalization
receptor catabolic process
cellular response to UV
regulation of ion transmembrane transport
T cell activation
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
glucocorticoid receptor signaling pathway
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
development involved in symbiotic interaction
positive regulation of protein catabolic process
positive regulation of nucleocytoplasmic transport
blood vessel morphogenesis
regulation of dendrite morphogenesis
regulation of synapse organization
progesterone receptor signaling pathway
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity

Function(s)

ubiquitin-protein transferase activity
protein binding
protein C-terminus binding
ligase activity
sodium channel inhibitor activity
protein domain specific binding
beta-2 adrenergic receptor binding
ubiquitin binding
phosphoserine binding
phosphothreonine binding
ubiquitin protein ligase activity
RNA polymerase binding
proline-rich region binding