RSS308057

• Gene Symbol: Map3k5
• Gene Name: mitogen-activated protein kinase kinase kinase 5
• Gene Aliases: Ask1, RGD1306565
• Chromosome Location: Chr.1: 15412039 - 15615050 on Build Rnor_6.0
• UniGene ID: -
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map3k5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001277694.1	NP_001264623.1	26	3829
	XM_008758622.1	XP_008756844.1	26	4693

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
activation of MAPK activity
positive regulation of protein phosphorylation
response to ischemia
protein phosphorylation
activation of cysteine-type endopeptidase activity involved in apoptotic process
JNK cascade
intrinsic apoptotic signaling pathway in response to oxidative stress
regulation of cell death
response to endoplasmic reticulum stress
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of JUN kinase activity
cellular response to hydrogen peroxide
programmed necrotic cell death
positive regulation of neuron death
cellular response to reactive nitrogen species

Function(s)

magnesium ion binding
protein kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
protein kinase binding
protein phosphatase binding
protein homodimerization activity