RSS315417

• Gene Symbol: Prox1
• Gene Name: prospero homeobox 1
• Gene Aliases: -
• Chromosome Location: Chr.13: 108382536 - 108444104 on Build Rnor_6.0
• UniGene ID: Rn.26557
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prox1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001107201.1	NP_001100671.1	2	2157
	XM_006250454.2	XP_006250516.1	2	2283
	XM_006250455.2	XP_006250517.1	2	1980
	XM_006250456.2	XP_006250518.1	2	2602
	XM_006250458.2	XP_006250520.1	2	2283

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell fate determination
kidney development
liver development
positive regulation of endothelial cell proliferation
lymph vessel development
lymphangiogenesis
lens development in camera-type eye
lens morphogenesis in camera-type eye
hepatocyte cell migration
transcription from RNA polymerase II promoter
brain development
circadian rhythm
positive regulation of cell proliferation
negative regulation of cell proliferation
regulation of gene expression
positive regulation of endothelial cell migration
dentate gyrus development
cerebellar granule cell differentiation
skeletal muscle thin filament assembly
lung development
pancreas development
response to nutrient levels
regulation of circadian rhythm
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of viral genome replication
endothelial cell differentiation
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
optic placode formation involved in camera-type eye formation
inner ear development
venous blood vessel morphogenesis
ventricular cardiac myofibril assembly
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
embryonic retina morphogenesis in camera-type eye
endocardium formation
positive regulation of sarcomere organization
ventricular septum morphogenesis
aorta smooth muscle tissue morphogenesis
positive regulation of heart growth
lymphatic endothelial cell differentiation
regulation of transcription involved in lymphatic endothelial cell fate commitment
branching involved in pancreas morphogenesis
lens fiber cell morphogenesis
hepatocyte differentiation
negative regulation of bile acid biosynthetic process
hepatocyte proliferation
acinar cell differentiation
neuronal stem cell population maintenance
positive regulation of cell cycle checkpoint
positive regulation of neural precursor cell proliferation
positive regulation of forebrain neuron differentiation

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
molecular_function
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
ligand-dependent nuclear receptor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
DBD domain binding
LBD domain binding