RSS319057

• Gene Symbol: Traf6
• Gene Name: TNF receptor-associated factor 6, E3 ubiquitin protein ligase
• Gene Aliases: -
• Chromosome Location: Chr.3: 91252829 - 91271607 on Build Rnor_6.0
• UniGene ID: Rn.220435
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Traf6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001107754.2	NP_001101224.1	7	1422
GenBank mRNA	BC168921.1	-	7	1422	9024408

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
ossification
neural tube closure
positive regulation of T cell cytokine production
protein complex assembly
immune response
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
JNK cascade
organ morphogenesis
protein ubiquitination
cytokine-mediated signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class II
osteoclast differentiation
positive regulation of lipopolysaccharide-mediated signaling pathway
activation of protein kinase activity
positive regulation of interleukin-2 production
T-helper 1 type immune response
positive regulation of T cell proliferation
odontogenesis of dentin-containing tooth
regulation of apoptotic process
myeloid dendritic cell differentiation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of JUN kinase activity
positive regulation of interleukin-12 biosynthetic process
positive regulation of interleukin-6 biosynthetic process
bone resorption
positive regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
bone remodeling
cell development
positive regulation of smooth muscle cell proliferation
T cell receptor signaling pathway
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
interleukin-1-mediated signaling pathway
protein K63-linked ubiquitination
response to interleukin-1
cellular response to lipopolysaccharide
positive regulation of transcription regulatory region DNA binding

Function(s)

ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
zinc ion binding
ligase activity
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
thioesterase binding
histone deacetylase binding
protein kinase B binding
protein N-terminus binding
ubiquitin protein ligase activity