RSS332369

• Gene Symbol: Irf1
• Gene Name: interferon regulatory factor 1
• Gene Aliases: -
• Chromosome Location: Chr.10: 39109530 - 39116532 on Build Rnor_6.0
• UniGene ID: Rn.6396
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Irf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012591.1	NP_036723.1	2	235
GenBank mRNA	BC076382.1	-	2	148	7099391
	M34253.1	-	2	235

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002198, BT019755, X14454, BC009483, AB103081, and others.
This siRNA also targets the following transcripts in Mouse: NM_001159393, NM_001159396, NM_008390, M21065, AK157347, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
cell cycle arrest
I-kappaB kinase/NF-kappaB signaling
female pregnancy
response to heat
regulation of gene expression
positive regulation of cell death
positive regulation of type I interferon production
positive regulation of interferon-beta production
regulation of MyD88-dependent toll-like receptor signaling pathway
cellular response to interferon-beta
regulation of cell proliferation
negative regulation of tyrosine phosphorylation of Stat1 protein
CD8-positive, alpha-beta T cell differentiation
positive regulation of interleukin-12 biosynthetic process
negative regulation of regulatory T cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
interferon-gamma-mediated signaling pathway
response to growth hormone
cellular response to mechanical stimulus
cellular response to retinoic acid
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to dsRNA
cellular response to peptide hormone stimulus
regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

regulatory region DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding