RSS339168

• Gene Symbol: Smad6
• Gene Name: SMAD family member 6
• Gene Aliases: -
• Chromosome Location: Chr.8: 68897746 - 68967219 on Build Rnor_6.0
• UniGene ID: Rn.42472
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smad6
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001109002.2	NP_001102472.1	2, 3	880
	XM_006243241.2	XP_006243303.1	2, 3	1991
	XM_006243242.2	XP_006243304.1	3, 4	1908

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008542, AF010133, AK046602, BC047280, AK004671, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

ureteric bud development
transcription, DNA-templated
immune response
transforming growth factor beta receptor signaling pathway
zygotic specification of dorsal/ventral axis
negative regulation of cell proliferation
negative regulation of SMAD protein complex assembly
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
cell-substrate adhesion
response to laminar fluid shear stress
intracellular signal transduction
negative regulation of apoptotic process
response to estrogen
fat cell differentiation
negative regulation of pathway-restricted SMAD protein phosphorylation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
molecular_function
chromatin binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ubiquitin protein ligase binding
type I transforming growth factor beta receptor binding
identical protein binding
transcription regulatory region DNA binding
co-SMAD binding
I-SMAD binding
R-SMAD binding
type I activin receptor binding