RSS339264

• Gene Symbol: Btk
• Gene Name: Bruton agammaglobulinemia tyrosine kinase
• Gene Aliases: -
• Chromosome Location: Chr.X: 105360922 - 105390580 on Build Rnor_6.0
• UniGene ID: Rn.26996
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Btk
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007798.1	NP_001007799.1	9	917
GenBank mRNA	AY787790.1	-	9	917
	FQ215667.1	-		1061

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000061, BC109080, AK057105, AK225577, X58957, and others.
This siRNA also targets the following transcripts in Mouse: NM_013482, L08967, L10627, L29788.

Gene Ontology Categories:

Process(es)

adaptive immune response
histamine secretion by mast cell
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
I-kappaB kinase/NF-kappaB signaling
response to organic substance
peptidyl-tyrosine phosphorylation
cell differentiation
cellular response to reactive oxygen species
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
protein autophosphorylation
cell maturation
T cell receptor signaling pathway
B cell receptor signaling pathway
cellular response to molecule of fungal origin

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
identical protein binding