RSS350538

• Gene Symbol: Park7
• Gene Name: parkinson protein 7
• Gene Aliases: CAP1, DJ-1, Dj1, SP22
• Chromosome Location: Chr.5: 167982438 - 168004724 on Build Rnor_6.0
• UniGene ID: Rn.30105
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Park7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001277249.1	NP_001264178.1	6	471
	NM_001277250.1	NP_001264179.1	6	471
	NM_001277251.1	NP_001264180.1	7	530
	NM_001277252.1	NP_001264181.1	6	411
	NM_001277253.1	NP_001264182.1	6	523
	NM_057143.2	NP_476484.1	6	653
GenBank mRNA	AF157511.1	-	6	653
	AF157512.1	-	6	407
	AJ007291.1	-	7	578
	BC091128.1	-	6	444	7376914
	FM055257.1	-	6	441
	FM061417.1	-	6	392
	FM069664.1	-	6	462
	FQ217993.1	-	2	100
	FQ220895.1	-	6	523
	FQ223564.1	-	6	521
	FQ224480.1	-	7	514

More Information

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
synaptic transmission, dopaminergic
negative regulation of protein kinase activity
proteolysis
protein deglycosylation
autophagy
inflammatory response
response to oxidative stress
mitochondrion organization
single fertilization
adult locomotory behavior
fertilization
detoxification of copper ion
negative regulation of gene expression
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
lactate biosynthetic process
negative regulation of protein ubiquitination
negative regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein sumoylation
cellular response to oxidative stress
cellular response to reactive oxygen species
cellular response to glyoxal
response to drug
response to hydrogen peroxide
hydrogen peroxide metabolic process
negative regulation of apoptotic process
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
regulation of TRAIL receptor biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
glycolate biosynthetic process
negative regulation of protein export from nucleus
regulation of inflammatory response
detoxification of mercury ion
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of ubiquitin-protein transferase activity
dopamine uptake involved in synaptic transmission
regulation of mitochondrial membrane potential
membrane depolarization
oxidation-reduction process
membrane hyperpolarization
negative regulation of cell death
regulation of androgen receptor signaling pathway
cellular response to hydrogen peroxide
positive regulation of protein homodimerization activity
positive regulation of protein localization to nucleus
negative regulation of neuron death
positive regulation of superoxide dismutase activity
negative regulation of protein acetylation
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of protein K48-linked deubiquitination
negative regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of pyrroline-5-carboxylate reductase activity
positive regulation of tyrosine 3-monooxygenase activity
positive regulation of dopamine biosynthetic process
glyoxal catabolic process
positive regulation of L-dopa biosynthetic process
positive regulation of L-dopa decarboxylase activity
negative regulation of oxidative stress-induced cell death
negative regulation of hydrogen peroxide-induced cell death
negative regulation of hydrogen peroxide-induced neuron death
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of reactive oxygen species biosynthetic process
negative regulation of ubiquitin-specific protease activity
positive regulation of oxidative phosphorylation uncoupler activity
positive regulation of transcription regulatory region DNA binding
positive regulation of androgen receptor activity
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

molecular_function
double-stranded DNA binding
single-stranded DNA binding
transcription coactivator activity
mRNA binding
receptor binding
copper ion binding
protein binding
transcription factor binding
peptidase activity
superoxide dismutase copper chaperone activity
oxidoreductase activity, acting on peroxide as acceptor
glyoxalase III activity
enzyme binding
kinase binding
cytokine binding
tyrosine 3-monooxygenase activator activity
L-dopa decarboxylase activator activity
identical protein binding
protein homodimerization activity
small protein activating enzyme binding
ubiquitin-like protein conjugating enzyme binding
mercury ion binding
androgen receptor binding
peroxiredoxin activity
repressing transcription factor binding
scaffold protein binding
cupric ion binding
cuprous ion binding
ubiquitin-specific protease binding
glyoxalase (glycolic acid-forming) activity