RSS350761

Gene Symbol:

LOC685590 Pik3ca

Gene Name:

similar to Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase p110 subunit alpha) (PtdIns-3-kinase p110) (PI3K)

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

Gene Aliases:

-

-

Chromosome Location:

Chr.X: 23243126 - 23258824 on Build Rnor_6.0

Chromosome Location:

Chr.2: 118831350 - 118861456 on Build Rnor_6.0

UniGene ID:

-

Rn.44193

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: LOC685590
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_008773148.1	XP_008771370.1	3	2613

Gene Symbol: Pik3ca
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_133399.2	NP_596890.2	16, 17	2493
GenBank mRNA	AF395897.1	-	4, 5	381
	CR754046.1	-	3, 4	309

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008839, BC089038, BC130228, AK051885, U03279.

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

glucose metabolic process
protein phosphorylation
positive regulation of peptidyl-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
regulation of multicellular organism growth
protein kinase B signaling
negative regulation of neuron apoptotic process
hypomethylation of CpG island
positive regulation of protein kinase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
negative regulation of fibroblast apoptotic process
regulation of genetic imprinting
negative regulation of anoikis

Function(s)

ATP binding
1-phosphatidylinositol-3-kinase activity
protein kinase activator activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity