RSS351273

• Gene Symbol: Gpx1
• Gene Name: glutathione peroxidase 1
• Gene Aliases: GSHPx, GSHPx-1
• Chromosome Location: Chr.8: 117117430 - 117118528 on Build Rnor_6.0
• UniGene ID: Rn.11323
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gpx1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_030826.3	NP_110453.3	1, 2	313
GenBank mRNA	BC058438.1	-	1, 2	285	6918849
	BI281978.1	-	1, 2	582
	CB579218.1	-	1, 2	313
	FQ211052.1	-	1, 2	310
	FQ227523.1	-	1, 2	342
	M21210.1	-	1, 2	319

More Information

Panther Classification:

Molecular Function -

peroxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
temperature homeostasis
endothelial cell development
negative regulation of inflammatory response to antigenic stimulus
lipid metabolic process
triglyceride metabolic process
glutathione metabolic process
apoptotic process
response to oxidative stress
response to lipid hydroperoxide
aging
sensory perception of sound
cell proliferation
intrinsic apoptotic signaling pathway in response to oxidative stress
response to xenobiotic stimulus
response to symbiotic bacterium
response to wounding
response to toxic substance
UV protection
response to hormone
response to glucose
response to selenium ion
response to gamma radiation
response to organic cyclic compound
myotube differentiation
protein oxidation
response to estradiol
response to hydroperoxide
regulation of mammary gland epithelial cell proliferation
response to nicotine
regulation of gene expression, epigenetic
vasodilation
response to hydrogen peroxide
hydrogen peroxide catabolic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
skeletal muscle tissue regeneration
regulation of neuron apoptotic process
blood vessel endothelial cell migration
fat cell differentiation
cell redox homeostasis
skeletal muscle fiber development
myoblast proliferation
response to folic acid
interaction with symbiont
positive regulation of protein kinase B signaling
heart contraction
angiogenesis involved in wound healing
regulation of proteasomal protein catabolic process
negative regulation of release of cytochrome c from mitochondria
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Function(s)

glutathione peroxidase activity
selenium binding
SH3 domain binding
glutathione binding
phospholipid-hydroperoxide glutathione peroxidase activity