RSS360218

• Gene Symbol: Btrc
• Gene Name: beta-transducin repeat containing E3 ubiquitin protein ligase
• Gene Aliases: beta-TrCP1
• Chromosome Location: Chr.1: 265100100 - 265270263 on Build Rnor_6.0
• UniGene ID: Rn.21800
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Btrc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001007148.2	NP_001007149.2	2	161
	XM_006231529.2	XP_006231591.1	2	744
	XM_006231531.2	XP_006231593.1	2	199
	XM_006231536.2	XP_006231598.1	2	196
	XM_006231537.2	XP_006231599.1	2	743
GenBank mRNA	BC085125.1	-	2	90	7131883
	CB584165.1	-	2	174
	EV771066.1	-	2	101

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AK188552, AK052317.

Gene Ontology Categories:

Process(es)

protein polyubiquitination
protein dephosphorylation
ubiquitin-dependent protein catabolic process
protein ubiquitination
protein catabolic process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
mammary gland epithelial cell proliferation
regulation of circadian rhythm
positive regulation of circadian rhythm
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
regulation of cell cycle
branching involved in mammary gland duct morphogenesis
regulation of proteasomal protein catabolic process
cellular response to organic cyclic compound

Function(s)

ubiquitin-protein transferase activity
beta-catenin binding
protein phosphorylated amino acid binding
protein dimerization activity
ubiquitin protein ligase activity