RSS368037

• Gene Symbol: Ascl1
• Gene Name: achaete-scute family bHLH transcription factor 1
• Gene Aliases: Mash1
• Chromosome Location: Chr.7: 28038662 - 28040504 on Build Rnor_6.0
• UniGene ID: Rn.32936
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ascl1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022384.1	NP_071779.1	1	1324
GenBank mRNA	X53725.1	-	1	1324

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_004316, BC001638, L08424, BC031299, AK290539, and others.
This siRNA also targets the following transcripts in Mouse: NM_008553, BC055748, AK141866, AK143210, M95603.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neuron migration
noradrenergic neuron development
noradrenergic neuron fate commitment
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Notch signaling pathway
regulation of mitotic cell cycle
pattern specification process
nervous system development
neuroblast fate determination
neuroblast proliferation
regulation of Notch signaling pathway
glial cell differentiation
response to lithium ion
regulation of gene expression
oligodendrocyte development
spinal cord association neuron differentiation
spinal cord oligodendrocyte cell differentiation
spinal cord oligodendrocyte cell fate specification
vestibular nucleus development
oligodendrocyte cell fate commitment
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
central nervous system neuron development
cerebral cortex development
neurogenesis
cell differentiation
neuron differentiation
regulation of epithelial cell differentiation
response to retinoic acid
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
neuron fate commitment
neuron fate specification
neuron development
generation of neurons
oligodendrocyte differentiation
regulation of neurogenesis
positive regulation of neurogenesis
musculoskeletal movement, spinal reflex action
response to folic acid
subpallium neuron fate commitment
regulation of timing of subpallium neuron differentiation
olfactory pit development
ventral spinal cord interneuron fate commitment
lung neuroendocrine cell differentiation
stomach neuroendocrine cell differentiation
carotid body glomus cell differentiation
adrenal chromaffin cell differentiation
sympathetic ganglion development
response to epidermal growth factor
cellular response to magnetism
positive regulation of neural precursor cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, transcription factor binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
bHLH transcription factor binding
sequence-specific DNA binding
E-box binding