VHS40179

• Gene Symbol: CDK1
• Gene Name: cyclin dependent kinase 1
• Gene Aliases: CDC2, CDC28A, P34CDC2
• Chromosome Location: Chr.10: 60778331 - 60794852 on Build GRCh38
• UniGene ID: Hs.732435
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CDK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320918.1	NP_001307847.1	8	1034
	NM_001786.4	NP_001777.1	8	1022
	NM_033379.4	NP_203698.1	7	851
	XM_005270303.3	XP_005270360.1	8	1104
GenBank mRNA	AK291939.1	-	8	959
	BC014563.1	-	7	893	2967728
	BC107750.1	-	8	1008	6710672
	BQ308742.1	-	1	489
	BT007004.1	-	7	880
	CR933728.1	-	7	3248
	D88357.1	-	6	736
	X05360.1	-	8	1006
	Y00272.1	-	8	1006

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007659, AK135516, BC005614, AK030231, AK051859, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
activation of MAPK activity
microtubule cytoskeleton organization
DNA replication
DNA repair
protein complex assembly
apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic nuclear division
mitotic nuclear envelope disassembly
mitotic G2 DNA damage checkpoint
centrosome cycle
pronuclear fusion
cell aging
response to toxic substance
positive regulation of gene expression
regulation of Schwann cell differentiation
response to organic cyclic compound
response to amine
response to activity
cell migration
histone phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
chromosome condensation
epithelial cell differentiation
organ regeneration
anaphase-promoting complex-dependent catabolic process
positive regulation of protein import into nucleus, translocation
protein localization to kinetochore
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
response to ethanol
positive regulation of DNA replication
positive regulation of mitotic cell cycle
regulation of embryonic development
response to cadmium ion
response to copper ion
response to axon injury
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
ventricular cardiac muscle cell development
positive regulation of cardiac muscle cell proliferation
cellular response to hydrogen peroxide
Golgi disassembly
positive regulation of protein localization to nucleus

Function(s)

protein kinase activity
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
RNA polymerase II carboxy-terminal domain kinase activity
cyclin binding
Hsp70 protein binding
histone kinase activity