VHS40628

• Gene Symbol: NFKBIA
• Gene Name: NFKB inhibitor alpha
• Gene Aliases: IKBA, MAD-3, NFKBI
• Chromosome Location: Chr.14: 35401510 - 35404754 on Build GRCh38
• UniGene ID: Hs.81328
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NFKBIA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020529.2	NP_065390.1	3	532
GenBank mRNA	AK311515.1	-	2	294
	AK313421.1	-	3	528
	AY033600.1	-	3	436
	BC002601.2	-	3	524	3161686
	BC004983.1	-	3	515	2957970
	BT007091.1	-	3	422
	M69043.1	-	3	516

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105720, FQ227283, FQ233200, FQ233557, X63594, and others.
This siRNA also targets the following transcripts in Mouse: NM_010907, BC046754, AK151608, U36277, AK151115, and others.

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
stimulatory C-type lectin receptor signaling pathway
apoptotic process
cytoplasmic sequestering of NF-kappaB
negative regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol efflux
negative regulation of lipid storage
viral process
lipopolysaccharide-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
positive regulation of cellular protein metabolic process
response to muramyl dipeptide
toll-like receptor 4 signaling pathway
response to muscle stretch
Fc-epsilon receptor signaling pathway
regulation of cell proliferation
regulation of NF-kappaB import into nucleus
cytoplasmic sequestering of transcription factor
negative regulation of apoptotic process
response to exogenous dsRNA
negative regulation of DNA binding
negative regulation of myeloid cell differentiation
negative regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
cellular response to cold
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
cellular response to cytokine stimulus
cellular response to organic cyclic compound

Function(s)

protein binding
transcription factor binding
nuclear localization sequence binding
enzyme binding
heat shock protein binding
ubiquitin protein ligase binding
protein complex binding
identical protein binding
NF-kappaB binding