VHS40651

• Gene Symbol: MAP3K10
• Gene Name: mitogen-activated protein kinase kinase kinase 10
• Gene Aliases: MEKK10, MLK2, MST
• Chromosome Location: Chr.19: 40191657 - 40215575 on Build GRCh38
• UniGene ID: Hs.466743
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAP3K10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002446.3	NP_002437.2	4	1392
	XM_006723222.2	XP_006723285.1	2	251
	XM_011526981.2	XP_011525283.1	4	1503
	XM_011526982.2	XP_011525284.1	4	1502
GenBank mRNA	X90846.1	-	4	1392
	Z48615.1	-	4	1264

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191621, XM_006228576.
This siRNA also targets the following transcripts in Mouse: NM_001290528, BC078445, BC046514, BC057197.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

apoptotic process
signal transduction
smoothened signaling pathway
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
positive regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of JUN kinase activity
negative regulation of transcription, DNA-templated
positive regulation of JNK cascade
protein autophosphorylation

Function(s)

transcription corepressor activity
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
ATP binding
protein homodimerization activity
bHLH transcription factor binding