VHS41387

• Gene Symbol: JAK1
• Gene Name: Janus kinase 1
• Gene Aliases: JAK1A, JAK1B, JTK3
• Chromosome Location: Chr.1: 64833223 - 65067746 on Build GRCh38
• UniGene ID: Hs.207538
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: JAK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320923.1	NP_001307852.1	21, 22	3058
	NM_001321852.1	NP_001308781.1	20, 21	3061
	NM_001321853.1	NP_001308782.1	22, 23	3320
	NM_001321854.1	NP_001308783.1	21, 22	3236
	NM_001321855.1	NP_001308784.1	21, 22	3239
	NM_001321856.1	NP_001308785.1	20, 21	2974
	NM_001321857.1	NP_001308786.1	20, 21	3152
	NM_002227.3	NP_002218.2	20, 21	3155
	XM_017001212.1	XP_016856701.1	20, 21	2999
GenBank mRNA	AB209057.1	-	19, 20	2911
	AB219242.1	-	18, 19	2802
	AK314257.1	-	21, 22	3059
	BC132729.1	-	19, 20	2873	40146751
	BX647675.1	-	6, 7	759
	HQ628631.1	-	18, 19	2835
	M64174.1	-	19, 20	2880

More Information

Gene Ontology Categories:

Process(es)

MAPK cascade
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
cell migration
cell differentiation
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
interleukin-2-mediated signaling pathway
regulation of cell proliferation
positive regulation of GTPase activity
innate immune response
response to antibiotic
interferon-gamma-mediated signaling pathway
regulation of interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
positive regulation of sprouting angiogenesis

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding