VHS41441

• Gene Symbol: SMURF2
• Gene Name: SMAD specific E3 ubiquitin protein ligase 2
• Gene Aliases: -
• Chromosome Location: Chr.17: 64542282 - 64662268 on Build GRCh38
• UniGene ID: Hs.515011
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SMURF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022739.3	NP_073576.1	10	1330
	XM_005257585.3	XP_005257642.1	9	930
	XM_011525128.1	XP_011523430.1	10	948
GenBank mRNA	AF301463.1	-	10	950
	AF310676.1	-	10	942
	AY014180.1	-	10	1130
	BC093876.1	-	10	1012	7939721
	BC111945.1	-	10	1014	8327413
	CR936721.1	-	11	1065

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
ubiquitin-dependent protein catabolic process
regulation of transforming growth factor beta receptor signaling pathway
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
Wnt signaling pathway, planar cell polarity pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of trophoblast cell migration

Function(s)

ubiquitin-protein transferase activity
transforming growth factor beta receptor binding
protein binding
ligase activity
identical protein binding
SMAD binding
ubiquitin protein ligase activity