n289093

• Gene Symbol: CFLAR
• Gene Name: CASP8 and FADD like apoptosis regulator
• Gene Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
• Chromosome Location: Chr.2: 201116015 - 201172688 on Build GRCh38
• UniGene ID: Hs.390736
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	10	8925
	NM_001202515.1	NP_001189444.1	6	7991
	NM_001202516.1	NP_001189445.1	8	8792
	NM_001202517.1	NP_001189446.1	9	8479
	NM_001202518.1	NP_001189447.1	8	9054
	NM_001202519.1	NP_001189448.1	9	9318
	NM_003879.5	NP_003870.4	10	8897
	XM_017005192.1	XP_016860681.1	10	9727
	XM_017005193.1	XP_016860682.1	10	11744
GenBank mRNA	AK124664.1	-	1	1097
	AK125394.1	-	1	1624
	AL365413.1	-	1	302

Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID	Transcript Location
GenBankmRNA	CF597105.1	-		114		Chr. - - [-] on Build

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis