n306874

• Gene Symbol: GDNF
• Gene Name: glial cell derived neurotrophic factor
• Gene Aliases: ATF1, ATF2, HFB1-GDNF, HSCR3
• Chromosome Location: Chr.5: 37812677 - 37840044 on Build GRCh38
• UniGene ID: Hs.248114
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GDNF
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000514.3	NP_000505.1	3	3087
	NM_001190468.1	NP_001177397.1	3	3107
	NM_001190469.1	NP_001177398.1	3	3029
	NM_001278098.1	NP_001265027.1	3	2915
	NM_199231.2	NP_954701.1	3	2932
GenBank mRNA	BC008580.1	-	1	693

More Information

Panther Classification:

Molecular Function -

neurotrophic factor

Gene Ontology Categories:

Process(es)

MAPK cascade
metanephros development
branching involved in ureteric bud morphogenesis
neural crest cell migration
organ induction
postsynaptic membrane organization
mesenchymal to epithelial transition involved in metanephros morphogenesis
signal transduction
nervous system development
positive regulation of cell proliferation
adult locomotory behavior
regulation of gene expression
postganglionic parasympathetic fiber development
peristalsis
neuron projection development
positive regulation of monooxygenase activity
positive regulation of dopamine secretion
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA stabilization
enteric nervous system development
sympathetic nervous system development
regulation of dopamine uptake involved in synaptic transmission
ureteric bud formation
regulation of morphogenesis of a branching structure
positive regulation of ureteric bud formation
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
regulation of stem cell differentiation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

Ras guanyl-nucleotide exchange factor activity
receptor binding
protein binding
growth factor activity
protein homodimerization activity