n366830

Gene Symbol:

CASC7 AGO2

Gene Name:

cancer susceptibility candidate 7 (non-protein coding)

argonaute 2, RISC catalytic component

Gene Aliases:

LINC00980

EIF2C2, Q10

Chromosome Location:

-

Chromosome Location:

Chr.8: 140520158 - 140642406 on Build GRCh38

UniGene ID:

Hs.660189

Hs.743313

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: CASC7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK092172.1	-	1	2252

Gene Symbol: AGO2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_011516965.2	XP_011515267.1	19	10490
	XM_011516966.2	XP_011515268.1	19	8231
	XM_011516968.2	XP_011515270.2	19	7565
	XM_017013317.1	XP_016868806.1	18	7183

More Information

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
translation
translational initiation
Wnt signaling pathway, calcium modulating pathway
post-embryonic development
RNA secondary structure unwinding
miRNA metabolic process
gene silencing by RNA
pre-miRNA processing
siRNA loading onto RISC involved in RNA interference
posttranscriptional gene silencing by RNA
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
phosphatidylinositol-mediated signaling
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
RNA phosphodiester bond hydrolysis, endonucleolytic
mRNA cleavage involved in gene silencing by siRNA
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Function(s)

RNA 7-methylguanosine cap binding
RNA polymerase II core binding
core promoter binding
double-stranded RNA binding
single-stranded RNA binding
mRNA binding
translation initiation factor activity
endoribonuclease activity
protein binding
protein C-terminus binding
siRNA binding
miRNA binding
poly(A) RNA binding
metal ion binding
endoribonuclease activity, cleaving siRNA-paired mRNA
endoribonuclease activity, cleaving miRNA-paired mRNA