s10056

• Gene Symbol: PAX2
• Gene Name: paired box 2
• Gene Aliases: FSGS7, PAPRS
• Chromosome Location: Chr.10: 100732940 - 100829941 on Build GRCh38
• UniGene ID: Hs.155644
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PAX2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000278.4	NP_000269.3	6	1329
	NM_001304569.1	NP_001291498.1	7	872
	NM_003987.4	NP_003978.3	7	1398
	NM_003988.4	NP_003979.2	6	1329
	NM_003989.4	NP_003980.3	6	1329
	NM_003990.4	NP_003981.3	7	1398
	XM_017016281.1	XP_016871770.1	9	3809
	XM_017016282.1	XP_016871771.1	9	3809
	XM_017016283.1	XP_016871772.1	9	3809
	XM_017016284.1	XP_016871773.1	8	3710
	XM_017016285.1	XP_016871774.1	8	3710
	XM_017016286.1	XP_016871775.1	7	3641
	XM_017016287.1	XP_016871776.1	7	3641
	XM_017016288.1	XP_016871777.1	7	3638
GenBank mRNA	AY153483.1	-	5	1607
	AY153484.1	-	1	53
	BJ989901.1	-	1	157
	L25597.1	-	6	1322
	M89470.1	-	6	1322

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001106361, XM_008760403, XM_006231443, XM_008760405, XM_008760404.
This siRNA also targets the following transcripts in Mouse: NM_011037, BC148232, BC150484.

Gene Ontology Categories:

Process(es)

urogenital system development
branching involved in ureteric bud morphogenesis
cell fate determination
mesonephros development
neural tube closure
optic cup morphogenesis involved in camera-type eye development
mesenchymal to epithelial transition involved in metanephros morphogenesis
retinal pigment epithelium development
transcription, DNA-templated
transcription from RNA polymerase II promoter
axonogenesis
mesodermal cell fate specification
aging
visual perception
glial cell differentiation
optic nerve development
optic nerve morphogenesis
optic nerve structural organization
vestibulocochlear nerve formation
response to nutrient levels
regulation of metanephros size
ureter maturation
pronephric field specification
inner ear morphogenesis
camera-type eye development
negative regulation of apoptotic process
negative regulation of programmed cell death
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of cytolysis
positive regulation of transcription from RNA polymerase II promoter
pronephros development
brain morphogenesis
stem cell differentiation
positive regulation of epithelial cell proliferation
oxidation-reduction process
mesenchymal to epithelial transition
optic chiasma development
cellular response to hydrogen peroxide
cellular response to retinoic acid
cellular response to glucose stimulus
cellular response to epidermal growth factor stimulus
metanephric mesenchyme development
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
metanephric mesenchymal cell differentiation
nephric duct formation
ureter development
metanephric collecting duct development
metanephric epithelium development
metanephric distal convoluted tubule development
metanephric nephron tubule formation
positive regulation of metanephric glomerulus development
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
regulation of metanephric nephron tubule epithelial cell differentiation
reactive oxygen species metabolic process
cochlea development
cochlea morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of mesenchymal cell apoptotic process involved in metanephros development
negative regulation of apoptotic process involved in metanephric collecting duct development
negative regulation of apoptotic process involved in metanephric nephron tubule development
negative regulation of reactive oxygen species metabolic process
positive regulation of metanephric DCT cell differentiation
positive regulation of optic nerve formation

Function(s)

core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
transcription factor binding
superoxide-generating NADPH oxidase activity
transcription regulatory region DNA binding