s10888 Validated

• Gene Symbol: PPARG
• Gene Name: peroxisome proliferator activated receptor gamma
• Gene Aliases: CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
• Chromosome Location: Chr.3: 12287850 - 12471054 on Build GRCh38
• UniGene ID: Hs.162646
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PPARG
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005037.5	NP_005028.4	2, 3	400
	NM_015869.4	NP_056953.2	2, 3	402
	NM_138711.3	NP_619725.2	3, 4	501
	NM_138712.3	NP_619726.2	3, 4	474
	XM_011533841.2	XP_011532143.1	2, 3	558
	XM_011533842.2	XP_011532144.1	2, 3	2435
	XM_011533843.2	XP_011532145.1	2, 3	2430
	XM_011533844.1	XP_011532146.1	3, 4	367
GenBank mRNA	AB307692.1	-	1, 2	227
	AB451337.1	-	2, 3	311
	AB451486.1	-	2, 3	311
	AB472042.1	-	3, 4	600
	AB565476.1	-	3, 4	494
	AJ563369.1	-	2, 3	271
	AJ563370.1	-	3, 4	327
	AJ698135.1	-	2, 3	295
	AK223528.1	-	1, 2	232
	AK290581.1	-	3, 4	399
	AL523434.3	-	3, 4	463
	BC006811.1	-	3, 4	348	3447380
	BG323933.1	-	3, 4	458
	BI820841.1	-	2, 3	437
	BM923992.1	-	3, 4	501
	BQ925271.1	-		462
	BT007281.1	-	1, 2	227
	D83233.1	-	2, 3	469
	DQ356894.1	-	1, 2	227
	HQ692866.1	-	1, 2	227
	KU178267.1	-	1, 2	227
	KU178268.1	-	1, 2	227
	U63415.1	-	2, 3	311
	U79012.1	-	2, 3	401
	X90563.1	-	2, 3	329

More Information

Matching Taqman Gene Expression Assay:

Hs00234592_m1

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
placenta development
negative regulation of acute inflammatory response
transcription initiation from RNA polymerase II promoter
lipid metabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
G-protein coupled receptor signaling pathway
heart development
response to nutrient
regulation of blood pressure
response to cold
response to mechanical stimulus
macrophage derived foam cell differentiation
negative regulation of macrophage derived foam cell differentiation
negative regulation of receptor biosynthetic process
negative regulation of cholesterol storage
negative regulation of sequestering of triglyceride
long-chain fatty acid transport
fatty acid oxidation
monocyte differentiation
negative regulation of cell growth
epithelial cell differentiation
response to caffeine
organ regeneration
response to retinoic acid
cellular response to insulin stimulus
negative regulation of collagen biosynthetic process
response to vitamin A
response to lipid
peroxisome proliferator activated receptor signaling pathway
response to immobilization stress
response to diuretic
glucose homeostasis
response to starvation
regulation of circadian rhythm
lipoprotein transport
steroid hormone mediated signaling pathway
response to estrogen
innate immune response
cell fate commitment
positive regulation of fat cell differentiation
low-density lipoprotein particle receptor biosynthetic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fatty acid oxidation
cell maturation
rhythmic process
negative regulation of smooth muscle cell proliferation
positive regulation of oligodendrocyte differentiation
white fat cell differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
negative regulation of telomerase activity
lipid homeostasis
response to low-density lipoprotein particle
positive regulation of phagocytosis, engulfment
negative regulation of interferon-gamma-mediated signaling pathway
regulation of cholesterol transporter activity
regulation of transcription involved in cell fate commitment
cellular response to retinoic acid
cellular response to vitamin E
cellular response to prostaglandin E stimulus
cellular response to hyperoxia
response to metformin
negative regulation of pancreatic stellate cell proliferation

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
prostaglandin receptor activity
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein phosphatase binding
estrogen receptor binding
ligand-dependent nuclear receptor transcription coactivator activity
activating transcription factor binding
identical protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
retinoid X receptor binding
arachidonic acid binding
alpha-actinin binding