s11137 Validated

• Gene Symbol: MAPK1
• Gene Name: mitogen-activated protein kinase 1
• Gene Aliases: ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
• Chromosome Location: Chr.22: 21759657 - 21867680 on Build GRCh38
• UniGene ID: Hs.431850
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAPK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002745.4	NP_002736.3	4	790
	NM_138957.3	NP_620407.1	4	790
GenBank mRNA	AK090869.1	-	5	647
	AK295188.1	-	6	723
	AK307615.1	-	5	635
	BC017832.1	-	4	790	4685557
	BC099905.1	-	4	755	5264558
	DQ399292.1	-	4	550
	EF565108.1	-	2	236
	Z11694.1	-	4	734
	Z11695.1	-	4	648

More Information

Matching Taqman Gene Expression Assay:

Hs00177066_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
MAPK import into nucleus
transcription, DNA-templated
protein phosphorylation
apoptotic process
chemotaxis
response to stress
cellular response to DNA damage stimulus
cell cycle
signal transduction
chemical synaptic transmission
axon guidance
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
response to toxic substance
positive regulation of peptidyl-threonine phosphorylation
regulation of phosphatidylinositol 3-kinase signaling
viral process
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
sensory perception of pain
cytosine metabolic process
platelet activation
positive regulation of cell migration
thyroid gland development
regulation of protein stability
lipopolysaccharide-mediated signaling pathway
positive regulation of telomere maintenance via telomerase
regulation of stress-activated MAPK cascade
mammary gland epithelial cell proliferation
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB signaling pathway
outer ear morphogenesis
response to exogenous dsRNA
response to estrogen
negative regulation of cell differentiation
positive regulation of translation
positive regulation of transcription, DNA-templated
thymus development
T cell receptor signaling pathway
B cell receptor signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of telomerase activity
Bergmann glial cell differentiation
long-term synaptic potentiation
face development
JAK-STAT cascade involved in growth hormone signaling pathway
lung morphogenesis
trachea formation
labyrinthine layer blood vessel development
cardiac neural crest cell development involved in heart development
ERK1 and ERK2 cascade
response to epidermal growth factor
caveolin-mediated endocytosis
regulation of Golgi inheritance
cellular response to granulocyte macrophage colony-stimulating factor stimulus
regulation of cellular response to heat
positive regulation of telomere capping
regulation of early endosome to late endosome transport

Function(s)

phosphotyrosine binding
DNA binding
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
transcription factor binding
RNA polymerase II carboxy-terminal domain kinase activity
kinase activity
phosphatase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding