s11140 Validated

• Gene Symbol: MAPK3
• Gene Name: mitogen-activated protein kinase 3
• Gene Aliases: ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
• Chromosome Location: Chr.16: 30114105 - 30123309 on Build GRCh38
• UniGene ID: Hs.861
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MAPK3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001040056.2	NP_001035145.1	5	861
	NM_001109891.1	NP_001103361.1	5	861
	NM_002746.2	NP_002737.2	5	861
GenBank mRNA	AK091009.1	-	4	1553
	AK307995.1	-	5	775
	AY033607.1	-	5	761
	AY033608.1	-	5	761
	BC013992.1	-	5	772	3634492
	BX537897.1	-	4	1552
	DQ399291.1	-	5	761
	KJ534878.1	-	5	761
	M84490.1	-	5	722
	X60188.1	-	6	833
	Z11696.1	-	5	689

More Information

Matching Taqman Gene Expression Assay:

Hs00385075_m1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
MAPK import into nucleus
positive regulation of protein phosphorylation
transcription initiation from RNA polymerase I promoter
protein complex assembly
protein phosphorylation
apoptotic process
DNA damage induced protein phosphorylation
cell cycle
axon guidance
fibroblast growth factor receptor signaling pathway
response to toxic substance
regulation of phosphatidylinositol 3-kinase signaling
viral process
phosphorylation
peptidyl-serine phosphorylation
sensory perception of pain
arachidonic acid metabolic process
platelet activation
BMP signaling pathway
thyroid gland development
positive regulation of cyclase activity
lipopolysaccharide-mediated signaling pathway
positive regulation of telomere maintenance via telomerase
regulation of stress-activated MAPK cascade
positive regulation of histone phosphorylation
positive regulation of histone acetylation
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
outer ear morphogenesis
response to exogenous dsRNA
positive regulation of translation
positive regulation of transcription from RNA polymerase II promoter
thymus development
regulation of sequence-specific DNA binding transcription factor activity
cartilage development
regulation of cytoskeleton organization
positive regulation of telomerase activity
Bergmann glial cell differentiation
face development
JAK-STAT cascade involved in growth hormone signaling pathway
lung morphogenesis
trachea formation
cardiac neural crest cell development involved in heart development
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
response to epidermal growth factor
cellular response to mechanical stimulus
caveolin-mediated endocytosis
regulation of Golgi inheritance
regulation of cellular response to heat
positive regulation of telomere capping
positive regulation of xenophagy
regulation of early endosome to late endosome transport
negative regulation of apolipoprotein binding

Function(s)

phosphotyrosine binding
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
kinase activity
phosphatase binding
scaffold protein binding