s11296 Validated

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• UniGene ID: Hs.25363
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000447.2	NP_000438.2	8	1154
	NM_012486.2	NP_036618.2	8	1154
	XM_005273199.3	XP_005273256.1	7	967
	XM_017001835.1	XP_016857324.1	7	1475
	XM_017001836.1	XP_016857325.1	7	967
GenBank mRNA	AF416718.1	-	6	795
	AK292299.1	-	9	1106
	AK301143.1	-	7	903
	BC006365.2	-	9	1348	4131408
	BT006984.1	-	6	727
	L43964.1	-	7	1094
	L44577.1	-	8	1092
	U34349.1	-	6	818

More Information

Matching Taqman Gene Expression Assay:

Hs01577197_m1

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding